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Prot 10, 10221037 (2015)

Future studies should prioritize large-scale, well-controlled clinical trials with optimized dosage forms and advanced delivery systems to validate efficacy, assess safety, and define appropriate treatment strategies

The new oral CCl 4 -induced moderate liver damage model closely resembles the pathophysiological features seen in human ALF, which makes it a good model for testing possible therapeutic interventions [17, 18]